Gene suppression in type 2 diabetes
Blocking the action of a gene called Sirtuin-1 reduced the symptoms of type 2 diabetes in rats, scientists have found.
The National Centre for the Three Rs has produced a handy 'beginners guide' to the 3Rs - Refinement, Reduction and Replacement - and how they can benefit science, innovation and animal welfare.
Targeting skin cancer
Using fish, scientists have discovered a signalling pathway that could be used to treat skin cancers (melanomas).
A tale of three species
The law of unintended consequences may have led to saving rabbits at the expense of a two incredible species: a prehistoric invertebrate and a small bird with one of the most impressive known migrations.
GM mice get Parkinson's disease
Researchers have created a GM mouse that develops Parkinson's disease.
Novel gene therapy reverses haemophilia
Scientists using mice have developed a new way to deliver gene therapies.
An Odyssey exploring the debate
A book to be published soon promises a considered, less polarised approach to the animal rights debate.
Protein culprit in Huntington's disease
Why does Huntington's disease lead to the death of brain cells, whilst causing negligible damage to cells elsewhere in the body?
Nanoparticles seek out plaques in arteries
Researchers have designed small particles - ‘nanoparticles' - that are able to selectively bind to plaques in arteries.
Effect of breast cancer gene reversed
Scientists have identified a gene implicated in up to one fifth of breast cancers. The good news is that studies in mice seem to show a commonly-used blood pressure drug appears to reverse the effects of the gene.
Pig cells transplant potential
Scientists have found a way to turn adult cells from pigs into any tissue in the body.
UK bioscience sector submits evidence to Lords
The House of Lords European Union Committee, Sub-Committee D (Environment and Agriculture) has begun to take oral evidence on the revision of the European Directive on animal experimentation
Japanese scientists produce fluorescing marmosets
Transgenic mice have been used in research for the last 20 years, and have made significant contributions to biomedical research.
Cold virus fights cancer selectively
Scientists have managed to modify the cold virus so that it only targets and damages cancerous cells.
Scientists link tumours to depression
Studies using rats have linked chemicals released by tumours with depression.
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