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Free eLearning resource on 'blinding' in animal experiments
The concept of blinding as a strategy to remove bias from experimental results
Postcards from the post-fact front line: Pseudoscience and non-sequiturs as a rationale against research
The reason the European Citizens’ Initiative failed is the reason anti-research campaigns are failing generally
Pain makes the heart grow stronger
Scientists working with both mice and people have found that painkillers could actually hinder the body’s recovery after a heart attack.
Nearly £1 million towards replacing cancer tests
Scientists have been awarded nearly £1 million to develop new test methods that should substantially reduce the numbers of animals used for testing chemicals which may cause cancer.
Gene therapy treats blindness in dogs
A common form of blindness has been successfully treated in dogs using gene therapy.
Nanoparticles boost vaccines
Scientists have developed nanoparticles that boost the effectiveness of vaccines in mice by mimicking part of the natural immune response.
Beagle breeding planning appeal fails
On Thursday 26 January, we learned that Communities Secretary Eric Pickles had agreed with the recommendations of a planning appeal inspector and dismissed the planning appeal by B&K animal breeders in East Yorkshire.
Rats jump aboard
On the principal that you can’t really understand something until you have tried it yourself, the UAR education team has been encouraging young people up and down the country...
Stem cells and heart repair
Continuing our video series on the patient benefits of animal research, a patient interviews a scientist on how stem cells, based on animal research, may be used to repair hearts.
Schizophrenia and sleeping problems linked?
Recent findings that a gene associated with schizophrenia also causes abnormal sleep patterns in mice have led scientists to ponder whether the mental illness and sleep disturbance could be genetically linked.
Worm holes and lung damage
New research suggests that understanding provided by parasitic worms could be used to treat serious lung injury caused by infections.
Omega-3 fatty acids protect against nerve damage
Scientists have found that omega-3 fatty acids can help speed up recovery from nerve damage.
Sex virus blamed for cancer rise
The UK Department of Health is being urged to review the national immunisation programme against cervical cancer, in response to a dramatic rise in throat cancer linked to oral sex.
One dog, 90 years, millions saved
Before January 1922, a diagnosis of Type 1 diabetes was in effect a death sentence; many died of starvation.
Cell walls can bock infections
Scientists have developed a new strategy for fighting infectious diseases.
Rare eye cancer pathway uncovered
Scientists have uncovered the secret behind the rapid progression of retinoblastoma, a rare type of childhood eye cancer.
Young blood treats old mice with MS
By transplanting cells from the blood of young mice, scientists have successfully stimulated stem cells to repair the damaged nerve tissue of old mice with multiple sclerosis.
HIV vaccine boost
Scientists have created a vaccine that protects rhesus monkeys from infection by the simian immunodeficiency virus (SIV), a relative of HIV, the virus that causes AIDS.
Gene could hold key to treating deafness
Scientists have identified a gene that, when deleted, causes deafness in mice.
Intricate experiments using mice have allowed scientists to visualise the formation of new brain circuits that form after birth.
Cancer treatment targets tumour growth protein
A chemical tested in mice, cell cultures and human biopsies has proved highly effective in preventing the growth of tumours.
Gene confers resistance to Marek’s disease
Scientists have identified a gene that appears to make chickens immune to the deadly Marek's virus - responsible for millions of deaths in chickens each year.
Tuning the immune system reverses MS
Scientists have found a way to reverse the devastating effects of multiple sclerosis (MS) in mice.
Weight loss treatment works in obese monkeys
Researchers have shown that a new compound can significantly reduce the weight of monkeys by destroying blood vessels that feed fatty tissue.
Vaccine protects mice against deadly Ebola virus
Scientists have developed a vaccine which protects mice from the Ebola virus and, unlike current vaccines, can be stored for long periods of time.
The Parliamentary Under Secretary of State for the Home Department, Lynne Featherstone, advanced an animal research policy based on evidence in a Commons debate on Wednesday 7 December.
World AIDS Day
It's 30 years since the first cases of HIV infection. During this time, says the website HIVaware, we've seen rapid change.
#WW award for Overlooking the Importance of Animal Research
We liked a piece in the Huffington Post by Kirk Leech. Overlooking the Importance of Animal Research in the UK politics section of the Huffington Post...
GM cells cure anaemia in mice
Mice have been cured of anaemia by an injection of genetically engineered cells that, when injected underneath the skin, formed blood vessels that secreted a hormone called erythropoietin.
Information tribunal rules for both sides
As anyone who reads it will see, a recent (11 November) Freedom of Information ruling falls some way short of the 'landmark decision' claimed by BUAV.
Naked mole rat DNA exposes its age-defying secrets
A team of scientists have begun to unravel the secrets underlying the long life enjoyed by naked mole rats.
Blood protein from rice treats rats
A human blood protein has been produced using genetically modified rice and used to treat liver disease in rats.
Release of leading extremists may inspire new attacks on animal research
Leading animal rights extremists Greg and Natasha Avery were released from prison this week.
Why don't woodpeckers get headaches?
How do woodpeckers avoid injury to their brain as their beak hits a tree at seven metres per second and up to 100 times per minute?
Blocking brain cancer in mice
An interaction between two proteins has been found to be essential for the development of the most common form of brain cancer.
#WW award for Of Mice and Medicine
We award Paul Vallely of the Independent newspaper for his excellent article - Of Mice and Medicine.
Modified protein treats haemophilia in mice
Scientists have engineered a human clotting factor into a safe and effective treatment that cured haemophilia in mice.
Chemotherapy delivered through the nipple
Tests in both rats and patients have shown that chemotherapy delivered through the milk ducts of the nipple is more effective and leads to fewer side-effects than intravenous drug delivery.
Lords again affirm support for animal research
Several peers confirmed their belief in the need for animal research in biomedical research, during a debate in the House of Lords yesterday (24 October 2011).
Of mice and medicine
Subtitled In defence of animal experiments, the Independent published a four-page article in Saturday's Magazine about how animal research is 'transforming human lives'.
New antibody protects monkeys from deadly Hendra virus
Squamous cell skin carcinoma is the second most common skin cancer after melanomas, affecting approximately 10,000 people in the UK each year.
Enzyme linked to miscarriages and infertility
Studies of patient tissue and experiments using mice have linked a specific enzyme to both infertility and miscarriage.
Sickle-cell anaemia treated in mice
Researchers have shown that they can treat sickle-cell anaemia in mice by switching on a haemoglobin gene usually only active before birth.
#WW award for Zebrafish article in Wellcome News
The article by Emma James in the latest Wellcome News looks into why zebra fish have become so important in genetics research.
Diabetes 'cured' with brain stem cells
Stem cells taken from a rat's brain using a simple procedure have been made to produce insulin and used to cure diabetes in the same rat.
Of mice and men - new video
Watch the 'Of Mice and Men' videos to see how GM mice are used to study human disease.
Less is more for common cancer treatment
A common cancer treatment has been shown to be more effective and less toxic when administered at more frequent, lower doses.
Lords affirm support for animal research
Members of the House of Lords on Tuesday affirmed their support for 'proper and appropriate' use of animals in medical research.
#WW award for NC3Rs review
Our Wedneday Winner today is the NC3Rs for producing a really clear, accessible and comprehensive review of the work it funds.
Cancer inducing protein protects against diabetes
Scientists have uncovered an intriguing signalling pathway linking cancer and diabetes.
The research they tried to stop
Three animal rights extremists who were imprisoned for their role in the 'Save the Newchurch Guinea Pigs' campaign – Jon Ablewhite, John Smith and Kerry Whitburn – have been released from prison.
Anti-viral medicine slows brain tumour growth
Scientists have found that the growth of Medulloblastoma brain tumour cells in mice can be significantly slowed using existing anti-viral medicines.
Mouse stem cells guided to become neuron-protecting cells
Scientists have successfully guided mouse stem cells to become specialised cells that build a protective coat around neurons.
How the brain communicates with the immune system
Experiments on mice have identified the missing link that allows the nervous and immune systems to communicate.
Neuron’s self-defence against dementia
Scientists have identified a signalling pathway used by neurons to protect against the cause of frontotemporal dementia, the second most common form of early-onset dementia after Alzheimer's disease.
Treating 'Alzheimer's disease' in mice
Scientists working with mice have identified a molecule that appears to cause the dementia suffered by Alzheimer's patients.
UK Bioscience Coalition position on the European Directive on animal research
Animal research is vitally important in science and medicine.
Replacing animals with nerves on a chip
A team of scientists have developed a way of guiding nerve cells to set up complicated networks that mimic the ones found in the brain.
#WW award for a letter from Parkinson's UK
Animal Aid is running a campaign against medical charities because some of their funded work involves animals.
'Glow in the dark' cats aids HIV research
Scientists inserted two genes into cats: the first is taken from macaque monkeys and helps the cat resist the feline form of Aids; the second is a fluorescent gene from jellyfish that helps the researchers literally see where the added anti-aids gene is active.
Colchicine from Crocus kills cancer
A modified version of a chemical found in the Autumn crocus has shown exceptional promise as a tumour-killing agent in mice and will soon begin clinical trials in humans.
See UAR at the BSA
UAR hosted and recorded a talk about GM mice - Of Mice and Men - by Sara Wells and Paul Potter from the Mary Lyon Centre (MRC Harwell) at this year's British Science Festival in Bradford. Watch the talk below.
Gene deletion blocks pain
Scientists have identified the gene that allows the transmission of chronic pain.
Safer treatment for sleeping sickness
Scientists have trialled a safer way of treating sleeping sickness in mice by modifying an existing medicine.
Modified bacterium protects against TB
Mice infected with a genetically modified relative of the tuberculosis bacterium became immune to tuberculosis, a new study has shown.
Computer model predicts effect of medicines on heart
Scientists have developed a computer model that predicts the effect of anti-arrhythmic medicines on the heart.
Stem cell treatment for stroke trial
A treatment developed in rats and mice has been shown to be safe in the first ever human trial of stem cell treatment for stroke victims.
Gene therapy hope for Menkes Disease
Studies in GM mice have shown that a combination of gene therapy and copper injections could be effective in treating Menkes Disease, a lethal and progressive disease that mainly affects young boys.
Gene mapping opens new insights into the brain
A map of gene activity has been created that scientists hope will shed new light on the causes of Alzheimer’s and Parkinson’s diseases.
Breakthrough against deadly Ebola virus
Scientists have uncovered the Achilles heel of the deadly Ebola virus; the breakthrough could lead to the first treatment for the tropical disease within a decade.
Obese mice fed artifical enzyme live longer
A new artificial enzyme(SRT1720) has been found to increase the lifespan of obese mice.
Gene therapy treats Duchenne muscular dystrophy
Modified stem cells have been used to treat Duchenne muscular dystrophy (DMD) in mice by replacing the faulty gene that causes the disease with a normal version of the gene.
Ear cells could be used in facial reconstruction
Tissue grown from stem cells taken from patients' ears could be used in facial reconstructions, tests in mice have shown.
Why fatty diet can lead to type 2 diabetes
Rates of diabetes have doubled in the last 30 years and doctors say rising levels of obesity are the main contributing factor.
#ww Buffering brains against stress
The hippocampus creates new neurones throughout our lives - so what happens if you bring "the hippocampus's production line to a screeching halt?"
Artificial protein could be 'universal' anti-viral
Antibiotics such as penicillin can be used to treat all sorts of bacterial infections, but doctors have few options when it comes to viral infections.
Some facts about Parkinson's and Alzheimer's research
The animal rights group Animal Aid launched an ill-informed, illogical and ill-conceived campaign against medical research charities a few weeks ago.
Mouse births from stem cell sperm
In the UK around 1 in 10 men are infertile, often because of low sperm counts.
Allergy testing with human cells
Allergic reactions to everyday chemicals are common causing eczema in millions of people, and tests on animals have been important in testing new chemicals for skin sensitisation.
Starving kidney cancer in mice
Researchers have identified a new chemical (STF-31) that selectively kills kidney cancer cells by blocking their glucose supply.
Cancer treatment for 'schizophrenic' mice
Schizophrenia is one of the most common serious mental health conditions in the UK, affecting 1 in 2000 people at some time in their lives.
Shining a light on ataxia
When people stagger after drinking too much ethanol has caused reversible ataxia – a loss of muscular co-ordination.
#ww Can scientists follow Laura’s lead?
Mark Henderson’s Science Matters column in today's Times Eureka gets our #ww Wednesday Winner award for communication about animal research (OK, it’s not Wednesday, but this column is a deserving winner).
Broken sleep disrupts memory
Research on mice has shown that uninterrupted sleep is vital for memory consolidation.
Coalition pledge on household product testing
This month’s awaited pledge by the coalition government to end household product testing on animals has been welcomed by the UK research community.
#ww award for the Ark Hive
Dr. Paul Foster, a Lecturer in Molecular Endocrinology at the University of Birmingham, is an experienced cancer researcher and pharmacologist with a strong interest in understanding how animals help advance medical research.
UK research using monkeys 'outstanding'
A report published today, called Review of research using non-human primates, recommends that scientific research on monkeys should continue in the UK, subject to rigorous safeguards.
I'm a scientist: get me in there!
For two weeks this June I took part in the 'I'm a scientist...get me out of here 2011' competition at the Wellcome Trust.
Animals containing human material
What are 'animals containing human material' (ACHM) and why the sudden interest in them?
Helping the hunt for disease genes
A few weeks ago it was announced that researchers have created genome-wide, high-resolution genetic maps of 100 inbred mouse strains.
Mice with human livers
To better study the breakdown and toxicity of new medicines in a human liver, scientists have created what has been named a ‘humanised mouse'.
Meningitis B vaccine one step closer
A study using mice has led scientists one step closer to developing a vaccine against the most common cause of bacterial meningitis, Meningococcus B.
Committing to the three Rs
The UK Home Office this morning agreed arrangements to deliver two Coalition commitments relating to the use of animals in scientific research
Spine repair allows rats to breathe again
Injuries that damage the spinal cord at the top of the neck can damage the nerve connections between the respiratory centre in the brain and the diaphragm muscles that we need to breathe normally.
#ww Animal models: Inside the minds of mice and men
Monya Baker has given us a good and useful read. Her article in Nature provides many examples of animal models for human conditions and gives a clear appraisal of their value.
UK animal procedures up by 3% in 2010
The UK Home Office has released figures showing that the number of research procedures using animals last year increased by 3% to just over 3.7 million.
Brain tumour growth slowed
Brain cancers caused by malignant gliomas account for around 3,000 deaths in the UK each year.
Polar bears and brown bears interbred
A genetic study of living and the ancient remains of polar and brown bears has revealed that they interbred during the last ice age and that modern polar bears are descended on the female side from brown bears that lived in Ireland.
Protein linked to cancer
Research in mice has shown how the over expression (over production) of a small protein allows cancer cells to divide.
Reversing Rett Syndrome in mice
New research using mouse models has shown that glial cells, which protect and support neurons in the brain, play a central role in preventing the severe symptoms of Rett Syndrome.
But can they suffer?
'The question is not can they reason nor can they talk, but rather can they suffer?' Jeremy Bentham
Millions owe their lives to animal research
Leading research organisations have responded to misleading claims made by an antivivisection group in its recent letter to the Lancet.
Cheap treatment for sleeping sickness
Researchers are preparing for clinical trials of the first inexpensive oral treatment for Trypanosomiasis, the parasitic disease commonly known as sleeping sickness that is transmitted to humans by the tsetse fly.
Gene repair treats haemophilia
About one in 30,000 boys are born with a defective gene that causes haemophilia B.
SchoolZone Goes Live
The UAR SchoolZone is a brand new part of our site dedicated to school age students and their teachers.
Animal research and diabetes
In this film we hear from Chloe, who has diabetes, and Dr Aileen King, who researches into diabetes.
#WW award for ... Animal research is helping us beat cancer
'Thanks to decades of research, survival from cancer has doubled in the last 40 years, giving thousands of people more time with their loved ones.
Vaccine shrinks prostate tumours in mice
A vaccine containing a broad spectrum of tumour antigens delivered in a virus vector successfully treated 8 out of 10 mice with prostate cancer.
Why do charities fund animal research?
The animal rights group Animal Aid has launched a campaign against medical research charities who fund animal research.
Chemical in apple peel strengthens muscle
An apple a day really does keep the doctor away according to a new study in mice.
New regulations will boost good science, promote animal welfare
New animal research regulations from Europe will enhance the welfare of animals, facilitate modern science and cut through excessive red tape.
CJD research potential for Alzheimer’s
Researchers working on treatments for the brain disorder Creutzfeldt-Jakob Disease (CJD) may have found a potential treatment for Alzheimer’s disease.
Heart repair initiated in mice
Human hearts cannot repair themselves after a heart attack damages heart muscle.
New mouse model for hepatitis C
The hepatitis C virus infects in the region of 170 million people around the world and creates an increased risk of cirrhosis, liver failure and cancer.
UAR in Mauritius
Macaques, like humans, are not indigenous to the island of Mauritius, isolated as it is in the Indian ocean.
Protein suppression stops leukaemia growth in mice
Leukaemia causing stem cells have been eliminated in mice by suppressing two proteins.
‘Trojan Horse’ brain cancer treatment increases lifespan
A novel ‘Trojan horse' method of treating brain cancer has increased the survival time of mice by one half.
BBC interviews UAR about beagle breeding plans
Animal rights protestors are targeting the beagle breeding company B&K Universal's plans for modernisation of their site in Grimston.
Targeting genes to stop breast tumours
Some breast cancers do not respond to currently available chemotherapy.
This months Wednesday Winner website (#WW) is Rodent Respect. The site was created for scientists who work with rodents, especially students.
Do-it-yourself animal research
It is often said that the only way to really learn anything is to do it yourself.
Armadillos infect humans with leprosy
Armadillos can infect humans with leprosy, according to a new study comparing the disease in US patients and armadillos.
Skin cancer protein identified in mice
Scientists have identified a protein that suppresses skin cancer in mice.
A history of Beecham’s
The story of Thomas Beecham, founder of the company that went on to become part of Glaxo SmithKline, is quite extraordinary.
Mouse model of human immune system validated
A mouse model of the human immune system has been validated by replicating the results of a recent human HIV clinical trial.
Prostate tumours reduced in mice
Prostate tumours have been in reduced in mice using a medicine originally designed to treat obesity.
Nine cell types to re-grow a fin
Understanding regeneration in model organisms gives hope that it may one day be possible for amputees to regrow limbs, or for heart attack patients to regrow healthy heart muscle.
Vulture decline slows
The ban on a veterinary medicine which caused an unprecedented decline in Asian vulture populations has shown the first signs of progress.
#WW - Untangling the brain
Our brains are a dense tangle of billions of nerve cells connected together at synapses. Knowing how everything links up is key to understanding how the brain works – but it's a huge challenge.
Vaccine protects monkeys against SIV
A vaccine has been developed that protects monkeys from Simian Immunodeficiency Virus (SIV), the monkey equivalent of HIV.
Creation of new Animal Welfare Centre in Scotland
The Scottish Agricultural College (SAC) is to coordinate a major, new, EU funded, research project to create a Centre of Excellence in Animal Welfare Science.
Number of nerve stem cells declines with age
A new study may explain why our brains produce fewer new neurons with age.
Antidepressants stimulate nerve cell growth
Stress can cause depressive illness in humans and has visible effects on mice such as failure to groom and weight loss.
Possible treatment for muscular dystrophy
About 100 boys are born with muscular dystrophies every year in the UK.
Technique mass produces neural stem cells
Stem cells hold the promise of cures for injuries such as spinal cord damage and diseases such as Parkinson's but producing large quantities of cells for experiments and clinical trials is proving very difficult.
How exercise protects the heart
Work with mice has shown that the elevated levels of nitric oxide produced during exercise protect the heart from injury during a heart attack.
European Chemical Agency call for animal test data
Chemical safety in Europe is regulated in part by REACH*.
#WW Wednesday Web award - Smallpox Through Time
In Elizabethan times smallpox killed more people than TB, leprosy, plague and syphilis combined.
How TB destroys lungs
GM mice have helped identify a key enzyme responsible for destroying lung tissue in tuberculosis (TB).
UAR appoints Interim CEO
The UAR Council is delighted to announce that, following a rigorous selection process, we have recruited David Pruce as Interim Chief Executive to ensure that our important work continues and thrives.
Aspirin may reduce effects of Prozac
Aspirin and other anti-inflammatory medicines taken for pain relief may reduce the effectiveness of antidepressants such as Prozac.
New hope for MS
Unlocking a key messenger protein in the body’s defences could be a first step to new treatments for multiple sclerosis (MS) and other autoimmune diseases, suggest studies in mice with a form of the disease.
Are wild animals happier?
Are wild animals happier? That was the question posed by Christie Wilcox for a guest blog in Scientific American.
Gene linked to lung cancer spread
Scientists have identified a genetic change that makes lung tumours more likely to spread to other parts of the body.
Growing new blood vessels in mice
Heart attacks and strokes could be prevented using a new method of blood vessel regeneration, according to research on mice.
Virtual rats' whiskers
A new computer model of rats' whiskers is helping scientists understand how rats process the sense of touch.
Genes temporarily turned-off
Scientists have created a new method to temporarily turn off the function of genes in mice.
Memory loss linked to stress
Scientists have discovered how stress contributes to memory loss in old rats.
Monkey malaria infecting humans
Monkeys infected with malaria are providing a reservoir of the disease from which humans can be infected.
UK public opinion largely positive
Recent research on public attitudes to animal experimentation has been published on the Ipsos MORI website.
A Question of Care
From our archive - this video about the care of laboratory animals was produced by the Biomedical Research Trust in 2003.
New mechanism links type-2 diabetes to obesity
Scientists have discovered a mechanism linking type-2 diabetes to obesity.
Stem cells for skin repair
New treatments for chronic wounds could be developed following the discovery of stem cells that repair damaged skin tissue.
Fish for Science is the first Wednesday Winner
We've awarded our first Wednesday award to The MRC Centre for Developmental and Biomedical Genetics for their Fish for Science website.
Genes for acute myeloid leukaemia
Scientists have identified three types of gene mutation that lead to acute myeloid leukaemia.
New skin cancer gene, new treatment
The discovery of a gene linked to skin cancer in zebrafish could lead to new treatments for the disease.
Be a Wednesday Winner #WW
We are starting our very own webby awards, which we are calling Wednesday Winners (#WW).
The teenager who took a stand against animal rights protesters
Laurie Pycroft, who founded Pro-Test five years ago, was profiled in The Independent Education section today.
European chemicals industry to develop non-animal toxicity tests
The European Chemical Industry Council (Cefic) has launched a £450,000 research project into finding non-animal methods of toxicity testing.
Multiple sclerosis reversed in mice
The process of nerve cell degeneration in multiple sclerosis (MS) can be reversed, according to new research in mice.
Protein linked to autism in mice
Research on GM mice has found how mutations in a single protein can lead to autism.
Jamie’s Dream School – animal madness?
In his science lessons for Jamie’s Dream School on Channel 4, Lord Winston showed the dramatic (in more ways than one!) impact that using animals can have in science lessons.
Optimising GM mouse research
'The MRC is absolutely committed to basic research and we understand the value of mouse genetics', said Professor Sir John Savill, CEO of the Medical Research Council today, announcing a multi-million pound investment in mouse genetics.
GM pig gets cystic fibrosis
A GM pig that gets cystic fibrosis is helping scientists understand the causes of the disease.
Mice sperm grown in the lab
Treatments for infertility in men could come from success in growing mouse sperm.
UAR makes a Big Bang
UAR teamed up with the Y Touring Company this month for a series of workshops about the use of animals in research at this year's Big Bang Science Fair held at London's Excel Centre.
RatCAP brain scanner
Scientists have developed a mini brain-scanner that allows them to study brain function and behaviour simultaneously in rats.
Did you know that it is exactly 100 years since a little-known researcher called Francis Peyton Rous in New York discovered that chickens could get cancer from viruses? We didn’t think so.
Mouse mimics another childhood brain cancer
Scientists have created a mouse model of the most common type of paediatric brain cancer.
Poor diet in pregnancy linked to diabetes in offspring
Poor diet during pregnancy could raise the risk of offspring developing diabetes, according to new research in rats.
New research suggests macaques experience self-doubt and uncertainty when making decisions.
Tiny sensors monitor heart attacks
The severity of a heart attack can be determined using tiny implanted sensors, according to new research on mice. Similar sensors could be used to monitor people at high risk of heart attack.
Black-footed kittens born through IVF
IVF has helped millions of couples achieve pregnancy, and not only in humans: it was with IVF that scientists recently produced these amazingly cute kittens.
Heart regeneration in newborn mice
Newborn mice can regenerate their own heart tissue following heart damage.
Mouse mimics childhood brain cancer
Scientists have created the first mouse model of a deadly form of childhood brain cancer.
Exercise reduces ageing in GM mice
Regular endurance exercise reduces the effects of ageing, according to new research on mice.
Artificial blood vessel success in animals
Artificial blood vessels for use in heart bypass surgery have been successfully tested in baboons and dogs.
New understanding of 'suspended animation'
Research on bears has extended our understanding of large mammal hibernation.
Enzyme reduces cancer spread
The spread of cancer to other organs has been reduced in mice by blocking an enzyme.
European medical science group states position on new law
The medical science group within the European Science Forum (ESF-EMRC) has produced a position paper on the new Directive on the Protection of Animals used for Scientific Procedures.
Spinal cord damage bridged in rats
Artificial ‘scaffolding' has been used to bridge spinal cord injuries in rats.
Wounds trigger tumours
Certain types of cancer could be triggered by simple wounds, according to new research on mice.
Kidney regenerator cell identified
Zebrafish are renowned in the science community for their ability to repair damage to heart muscle.
Watch and read - Where do medicines come from?
We've produced a new leaflet and accompanying video that is being distributed to GP waiting rooms throughout the UK for the next six months.
Enzyme linked to blindness
Age-related macular degeneration (AMD) has been linked to the lack of a protective enzyme in the retina.
HIV-like virus cured in mice
Scientists have used a hormone to completely remove a HIV like virus from mice.
Protein predicts cancer spread
Scientists have identified a protein that tumours make when they are likely to spread.
Cancer medicine could treat spinal injury
The cancer medicine Taxol has been used to treat spinal injury in rats.
Gut bacteria affect brain development
Bacteria in the gut acquired early in life could affect future brain development and behaviour, according to new research on mice.
Hormone improves memory in rats
A hormone has been found that boosts the memory of an unpleasant experience in rats.
Lack of omega-3 linked to mood disorders
Mice fed a diet lacking in the fatty acid omega-3 are more susceptible to mood disorders, according to new research.
Tiny camera reveals brain changes in real time
An innovative new instrument has been developed that enables scientists to observe changes deep inside the brains of animals.
Caffeine could cure hangover headaches
Caffeine and painkillers could be the most effective cure for a hangover headache, suggests new research on rats.
Fighting cancer with cancer
An innovative new approach to fighting cancer has reduced tumour size in mice.
New video - mice as a model for Alzheimer's disease
Mice can be used to mimic Alzheimer's disease in humans.
RNA based medicine for HIV
A potential RNA based treatment for HIV is showing positive results in tests on mice.
UK scientist wins prize for improving animal welfare
Each year the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) awards a prize for innovative research which has an impact on the use of animals in life sciences.
UAR CEO moves to SGM
Dr Simon Festing, the Chief Executive of Understanding Animal Research for a little over six years, is leaving the organisation to take up the post of CEO of the Society for General Microbiology (SGM).
Scientists closer to MRSA vaccine
Scientists are closer to developing a vaccine against the superbug MRSA.
MicroRNA combats prostate cancer
Small strands of RNA, called microRNA, inhibit prostate cancer stem cells in mice.
Zebrafish grow abnormally in microgravity
Zebrafish raised in microgravity, replicating the conditions of space, develop skull defects.
GM chickens prevent transmission of bird flu
Bird flu epidemics could be prevented by GM chickens that stop the spread of flu to other birds.
Artificial intestine reduces animal tests
An artificial human digestive system is replacing the use of animals in some tests to see how medicines are absorbed, The Times reported last week.
Stem cells could end blood platelet shortage
Blood platelets produced from embryonic stem cells have been used to repair damaged tissues in mice.
Vaccine induces cocaine immunity in mice
Cocaine immunity has been induced in mice using an altered version of the common cold virus.
Genetic modification strengthens hearts
Mice have been genetically modified to grow stronger hearts.
Horse genital cancer virus identified
Scientists have discovered a virus linked to genital cancer in horses.
Mechanism behind autism uncovered
Nerve cells that are unable to communicate effectively may be responsible for autism spectrum disorders (ASDs), according to new research on mice.
Rats sniff out tuberculosis
Gambian pouched rats are being used by scientists to sniff out tuberculosis in mucus samples.
Zebrafish improve understanding of cancer growth
Experiments on zebrafish larvae have revealed how cancer cells harness the immune system to quicken the spread of the disease.
Art meets science in mouse's brain
Animals have been used to understand the inner workings of the brain since the very beginnings of neuroscience.
How you live now impacts on the children you have yet to conceive
Smoking or drinking while pregnant can damage the unborn child.
World-leading research institute gets go-ahead
We are pleased to report that planning permission was granted last week for a new world-leading biomedical research institute in London.
Alzheimer’s reversed in mice by memory protein
Memory loss has been reversed in Alzheimer's mice by boosting levels of a memory related protein.
Childhood flu may protect against asthma
Exposure to bacteria or viruses as child could reduce your chances of contracting asthma, according to new research on mice.
Stem cells combat muscular dystrophy
A new mouse model of muscular dystrophy has found that stem cells play an important role in this genetic disease.
Freedom of Information - judgement on confidentiality clause at a university
Recently, a tribunal ruled that under the Freedom of Information Act a university can be said to 'hold' project licences (irrespective of how they are actually stored at the university) and that section 24 of the Animals (Scientific Procedures) Act 1986 (ASPA) would not prevent disclosure of information from the project licences.
Biological clock pigment could help blind people
Light sensing cells (photosensitive ganglion cells) in the eye, which contain the pigment melanopsin, set the body's biological clock.
Following directly from the Basel Declaration that we covered on Tuesday, an editorial in Nature, 9 December 2010, has urged German science to set up an organisation like Understanding Animal Research to engage the public on the medical benefits of animal research.
Dementia confuses memories
Confused memories rather than memory loss may be the cause of 'forgetfulness' in dementia patients, according to new research.
Enzyme causes chronic pain
An enzyme responsible for making pain last after nerve injury has been discovered in mice.
Winter birth may alter biological clock
Being born in winter could make your long-term biological clock tick slower, according to a new study on mice.
Basel Declaration calls for open dialogue
More than 50 top scientists working in Germany and Switzerland have launched a new Declaration about animal research.
Focus on fluorescent filming
The Scientist reported on its top ten life-science innovations for 2010 this week.
Scientists create 'couch potato' mouse
By removing a protein that muscles use to convert fuel into energy, the researchers produced a mouse with normal body weight but which did not have enough energy to exercise.
How much effort on alternatives? The answer is a lot
Our attention was drawn this week to a relatively new European initiative called AXLR8, a consortium which aims to accelerate progress in developing alternatives to animals for safety testing.
Ageing reversed in mice
Premature ageing can be reversed in mice, hinting at the possibility of anti-aging treatments for humans.
World AIDS Day - 1 December
The HIV & AIDS page on our partner website AnimalResearch.info has been updated to mark World AIDS Day on 1 December.
Infiltration: most allegations unfounded
Understanding Animal Research today (Tuesday 30 November) welcomed a report from the Home Office addressing claims by an animal rights group about animal research and testing at a UK facility in 2009.
New European law marks dawn of a new era
The new European Directive 2010/63/EU on animal experimentation has been finalised.
New video: Why do we use animals in research?
In this short interview with Dr Simon Festing, we hear his response to questions such as: Why is their so much secrecy in animal research?
Changing nerve cells could treat spinal injury
Nerve cells made from a person's own skin suggest a novel way to treat spinal injury.
Compound controls weight and blood sugar
A new compound has been designed that controls weight and blood sugar in mice, raising the prospect of a treatment for sufferers of obesity and diabetes.
Shining a light on depressive disorders
Depression and anxiety affect a significant proportion of the British population, yet the underlying causes behind these medical disorders remain elusive.
How familiarisation breeds contempt
How do we learn to recognise new sensations and distinguish them from those we are already familiar with?
Blood pressure medicine could treat Alzheimer’s
A medicine previously used to treat high blood pressure could now be applied to Alzheimer's disease following tests on GM mice.
Pregnant mice point to treatment for premature labour
Scientists have found that the onset of labour is controlled by tiny molecules called microRNA.
World Diabetes Day - 14 November
World Diabetes Day (WDD) is the primary global awareness campaign of the diabetes world.
GM mouse immune to cancer
Cancer tumours somehow escape the body's immune system, even when that immune system is primed by a vaccine designed to specifically target the cancer.
Gene mutation increases dementia
The dementia associated with Alzheimer's and Parkinson's diseases is commonly associated with abnormal clumps of a protein (B-synuclein) in the brain.
Mice treated for memory loss
Mice treated with a brain enzyme inhibitor performed better in memory tests than untreated mice.
New government committed to continued crackdown
Following the sentencing of six animal rights extremists on Monday, the new government made clear that it remains committed to countering criminal activity carried out in the name of animal rights.
New video - How much animal research in the UK?
A new video, How much animal research is done in the UK, is now available in our youtube site and in the video section in the resources page on this website.
Deadly rinderpest virus eradicated
The UN has just announced that rinderpest, a virus that used to cause deadly outbreaks in cattle, has been eradicated in the wild.
Congenitally deaf cats have better peripheral vision
When the brain is deprived of input from one sense it often compensates with above normal performance in another sense.
Elixir of life?
Supplementing the diet of healthy middle-aged mice with a mixture of amino-acids - the building blocks of proteins - extended their average lifespan by over one tenth.
Potential treatment for terminal cancer
For the first time, researchers have discovered a therapy that can treat the invariably lethal terminal stages of cancer in animals.
The top 100 scientists in Britain today
The first list of its kind for science, The Eureka 100: The Science List by The Times last week aimed to identify the 100 most important people in British science.
European statistics on animal research released
The overall number of animals used in research across European member states does not seem to have changed much since 2005, standing at just above 12 million in 2008 (a decrease of 116,561 since 2005).
Mice muscles controlled by light
How do you re-animate paralysed limbs? A new approach being trialled on genetically modified mice uses flashes of light.
No retirement for chimp colony
186 chimps currently housed in unofficial retirement in the Alamogordo Primate Facility in New Mexico are to be re-housed in the Southwest National Primate Research Center.
Mice and monkeys metabolise BPA like humans
New research shows female mice, monkeys and humans appear to metabolise the oestrogen-like chemical bisphenol A (BPA) in similar ways.
Free course on science communication
The National Science Learning Centre in York is offering a fantastic opportunity to improve your science communication skills with a two-day course on engagement with schools and young people on 18-19 October 2010.
EU directive on animal research becomes law
Yesterday the President of the European Parliament, and the Belgian State Secretary (representing the EU countries) put pen to paper and signed the new EU Directive 8869/10 in the use of animals in scientific research.
Retinal cells transplanted into blind mice
Retinal cells, necessary for colour vision, have been successfully transplanted into blind mice.
Loss of gene makes mice smarter
Mice with a disabled RGS14 gene are able to remember objects and learn to navigate mazes better than normal mice.
Tasmanian Devil genome sequenced
The Tasmanian Devil is at risk of extinction in the wild due to a transmissible cancer passed on when one animal bites another.
Drug reverses diabetes nerve damage
Diabetes can cause the death of nerves in the body's extremities, a condition known as diabetic peripheral neuropathy (DPN).
Single gene regulates motor neurons in the spinal cord
As a normal mammalian body grows, hundreds of motor neurons grow from the spinal cord to the muscles they will control.
Support for research that uses animals containing human material
The public broadly supports research on animals containing human material, according to an Ipsos Mori survey of 1,042 people.
European parliament votes on animal research directive
Today the European Parliament agreed on the final text of the new Directive concerning the use of animals in research.
Anti-clotting medicine attacks lupus
Lupus is a chronic disease where the body's own immune system attacks healthy tissue, causing inflammation, pain and damage in organs, particularly the kidneys.
How fish oils reduce inflammation
The omega-3 fatty acids DHA and EPA found in oily fish reduce inflammation, which in turn reduces the symptoms of arthritis and reduces the risk of heart attacks and strokes.
Rat pancreas grows in mouse
An ultimate goal of regenerative medicine is the generation of organs derived from a patient's stem cells.
Why older women fail to conceive
As women get older the chances of infertility, birth defects and developmental disabilities go up.
Malaria cured in mice
Increasing resistance to anti-malarials, such as those based on Artemisinin, have prompted a need for new treatments.
Resetting body clock in mice
Researchers have successfully used a chemical to reset and restart the natural 24-hour body clock in mice.
New approaches to animal research in schools
Animal research is a favourite topic when teachers are looking for a sure-fire way to get their students interested in the ethics of science, but are schools getting all they can from this complex, sometimes difficult, always fascinating subject?
Monkeys survive lethal Ebola and Marbug
Monkeys treated with a therapy that targets specific viral genes survived deadly Ebola and Marbug infections, a new study reports.
Magnetic medicines treat brain tumours
The barrier between blood vessels and the brain may no longer limit the delivery of medicines to tumours, research on rats shows.
Shellfish toxin testing
The recently published Annual report (2009) of the Animals Scientific Procedures Inspectorate and Division highlights progress towards suitable alternatives to replace the use of mice in the testing for toxins in shellfish.
UGUST 20, 1960: MOSCOW The Soviet Union today launched its second cosmic space ship, the Soviet news agency, Tass, said. The space ship carries animals, including two dogs.
GM rats promise better disease models
Scientists have created a ‘knockout rat' that can be used to model certain diseases in the same way as mice.
Chillis may reduce blood pressure
Capsaicin, a compound found in chilli peppers, has been found to reduce high blood pressure in rats.
Mouse clues to testicular cancer
For the first time scientists will be able to study the development of human testes in mice.
'Home grown' joints
The body's own cells could be used to aid the repair of joints, a pioneering rabbit study has revealed.
Puma may aid tumour growth
A study on mice suggests that cell suicide may encourage tumours to grow instead of destroying them.
Mouse research has revealed a link between bone remodelling, blood sugar and diabetes.
7,000 and counting...
Are you a school science teacher or a GCSE science student? Don't miss out next year - invite a volunteer speaker into your schoo
Genetically altered animals overtake normal animals in UK research
The UK government announced this morning that the number of animal procedures in 2009 fell by 1% compared with the previous year.
Ferrets, flu, fish and pharmaceuticals
Grants worth £4 million have just been announced for 13 science projects that aim to minimise the use of laboratory animals and improve their welfare.
Down syndrome: two genes crucial
Some of the symptoms relating to Down syndrome have been linked to two genes on chromosome 21, a study on mice has shown.
Protein linked to heart failure
Elevated levels of the protein CIB1 causes enlargement of the heart and subsequent heart failure, according to rodent research.
Primitive cells help blind mice see
Primitive retinal cells, that were previously thought to have no role in image formation, can help blind mice see.
Scientists watch armed immune cells fight cancer
Armed and tagged immune cells can be watched attacking tumours in mice in real time.
A light on Parkinson's
Shining a laser into the brain may ease the symptoms of Parkinson’s, a new study in mice has shown.
A pill that could reverse Alzheimer’s
A new compound that may reverse Alzheimer’s in humans has proven successful in rats and mice.
Physical, social stimulation may starve tumours
Mice with cancer living in enriched environments had smaller tumours, new research has revealed.
Artificial lung an alternative test-bed?
A functional artificial lung on a chip, which mimics the behavour of mouse lungs, has been created.
Cancers linked by faulty gene
Prostate cancer and hereditary breast cancer could be linked by the same gene, research on mice suggests.
New guidelines for reporting research
The National Centre for the Reduction, Refinement, and Replacement of animals in research (NC3Rs) has published a list of guidelines for scientists to follow when reporting the results of research involving animals.
UK Bioscience Sector outlines principles for implementing new Directive
The UK Bioscience Sector has produced a set of principles for the implementation and transposition of the revised EU Directive concerning the use of animals in research.
European public opinion divided
The European Commission has published a survey on the public's opinion of science and technology.
Rats breathe using lab lungs
For the first time rats have been able to breathe using lab grown lungs, a new study reports.
What R you watching? An interactive resource for schools
What R you watching? our latest online interactive educational resource, is now live on the UAR site.
A guide for UK institutions on the new EU Directive
The revised European Directive on animal research (EU8869/10) should be formally 'adopted' in Europe during summer 2010.
Weakened virus makes better vaccine
Rewriting the genetic code of the flu virus has helped to produce a stronger immune response, studies on mice have shown.
Gut bacteria may trigger arthritis
A novel study has uncovered a link between stomach bacteria and the development of rheumatoid arthritis in mice.
Painkiller from sea snail venom
A new painkiller is 100 times more potent than other painkillers, tests on rats have revealed.
Liver grafts grown in the lab
Scientists are a step closer to producing artificial livers after successfully producing a rat liver graft from stem cells.
Plastic antibodies attack bee stings
Immune system molecules made from plastic have functioned successfully in the first tests involving mice.
UK government minister to discuss animal research policy
The Home Office minister with responsibility for animal research, Lynne Featherstone, has agreed to meet the bioscience sector to discuss policy issues.
Canine cancer consortium
Two organisations have joined together to further research into canine cancer.
Extra chromosome protects against cancer
An extra copy of chromosome 21 may boost protection against cancer, research on mice suggests.
Scar tissue process revealed
Research on mice has revealed the process which limits the accumulation of excessive scar tissue.
The ultimate mouse gene study
A global effort announced recently could lead to the ultimate mouse model of human disease. The International Mouse Phenotyping Consortium (IMPC) aims to explain and share the functions of genes in mice.
The Marks & Spencer bunnies
Some may have seen the full page advert by the retailer Marks & Spencer (M&S), with pictures of rabbits, proclaiming its commitment not to test cosmetics or household products on animals.
The Animal Protection Party and the UK General Election
Just over a month has passed since the 2010 General Elections and the resulting Coalition government is beginning to outline their new policies.
Tremors caused by spinal malfunction
The mechanism which causes severe tremors in people with Parkinson's disease could be controlled through the spine, research on monkeys suggests.
RSPCA and LASA produce new guidelines
Ethical Review Process (ERP) bodies within animal research institutions now have the tools to "develop more efficient and effective processes".
Mystery of lithium action solved
The mechanism by which lithium works to reduce inflammation in the brain has been discovered in a study on rats.
New grants for science teachers
No understanding of how science works is complete without some knowledge of the way we use research animals.
Stem cell hope for deafness
Growing hair cells from stem cells could offer personalised treatments for deafness in the future, scientists studying mice suggest.
Dogs knees hold sporting injury clue
Canine genetics may be able to explain why both humans and dogs develop ligament injuries.
New treatment targets source of asthma
Lowering the production of specific immune cells could prevent asthma attacks, research on mice shows.
Council agrees stricter rules for animal experimentation
The European Council of Ministers has announced agreement on the draft Directive for the Protection of Animals used for Scientific Purposes.
Pigs are a new ideal model for cystic fibrosis
The cause of cystic fibrosis (CF) is becoming clearer after scientists used pigs as models instead of mice.
First trials for stem cell transplant into human spine
Stem cells have been injected into the human spine in a pioneering trial to test the safety of the technique, with the hope of treating a debilitating neurodegenerative condition.
Broccoli chemical kills cancer cells
A chemical in broccoli can kill breast cancer cells and halt tumour growth, accroding to new research on mice.
Hormone injection fights bone death
Bone death, a side effect of steroid medication, could be prevented according to new studies using rabbits.
Chilli-like chemical part of the pain pathway
A group of substances similar to those that give chillies their kick are part of the body's pain mechanism, research on mice has shown.
Study points to new cell culprit for epilepsy
In the past, research on epilepsy has focused on nerve cells, or neurons.
Artificial skin graft success
Artificial human skin developed in the laboratory has been successfully grafted onto mice.
Parties outline their stances on animal research
As the election manifestos from the political parties have been published, we have been having a look to see what they have to say about animal research.
Tribunal rules in favour of UK University in FOI case
A Freedom of Information (FOI) request made nearly three years ago has reached its conclusion, at least for now, with a ruling by the Information Tribunal.
Antifungal drug reduces tumour size
A medicine currently used to treat fungal infections successfully slows tumour growth in mice, according to new research.
Duck gene helps fight flu in chickens
Influenza protection can be transferred across species, say scientists who have identified a key gene in ducks.
Fat-free proteins kill tropical disease bug
Parasites which cause sleeping sickness can be killed by altering the proteins that they are dependent on, studies on mice show.
Agreement on European regulation
The European Parliament and Council representatives have reached an agreement on the final details of the revisions made to Directive 86/609/EEC on animal experimentation.
Enzymes are target for lung cancer treatment
‘Switching off' certain enzymes helps reduce tumours in mice, research has shown.
Synthetic ‘organ' helps stop gout
A plastic capsule implanted under the skin could help regulate metabolic processes, a study on mice has revealed.
RSPCA and GCSE science
The RSPCA's latest foray into schools education is a smart new web resource for GCSE science with a substantial chunk dedicated to exploring the ethics of animal research.
3Rs in front of the camera
If there is one thing that anti-vivisection campaigns are good at, it's providing vivid imagery.
Retrial for animal rights activist?
An animal rights activist who was jailed last year for a firebombing plot against Oxford University in 2006 faces a retrial.
Walnuts to fight prostate cancer
Eating walnuts as part of a balanced diet may reduce the size and growth of prostate tumours, a study on mice has shown.
Glaucoma begins with brain nerve deterioration
Damaged nerves in the brain are the cause of the eye disease glaucoma, rather than damage to the eye itself as was previously thought. This recent finding was the outcome of research using mice.
Faster repair for damaged bones
Stem cells can help repair severely damaged bones quickly, studies on sheep and humans have revealed.
Absent gene heals mice without scarring
Mice lacking the p21 gene can be healed scar free, a study has shown.
Mice vote Green
Simon Jenkins, writing in The Guardian on Friday, asserted that giving animals rights leads to moral chaos. His piece, both amusing and serious, alludes to a recent bit of fun in the pro-hunting magazine, Country Life, which speculates about which political party different animals would vote for.
Tapeworm vaccine helps pigs and humans
A new vaccine successfully blocks tapeworm infection in pigs, helping to break the cycle of infection between pigs and humans.
FoI and lessons for records management
Freedom of Information (FoI) requests have recently been in the news, as many UK Universities have received a request for information from Luke Steele, an animal rights activist based in Yorkshire.
UK public attitudes - not much change
Public opinion research released this week shows that public attitudes to animal research haven't changed much in the UK over the last few years.
Mouse model develops human liver
Mice could be more useful in the study of hepatitis than previously thought, as research into the possibility of growing a human liver in a mouse has proven successful.
This little piggy
There are some strange animal-related things happening in Europe, but sometimes sense can prevail.
New cause of diabetes revealed
Pig models are becoming increasingly important in medical research into the causes of diseases, and have now shed new light on the causes of diabetes.
TB and leprosy resistance gene link
A new gene variant that increases resistance to diseases such as tuberculosis (TB) and leprosy, has been identified from studies on zebrafish and humans.
Stomach hormone helps reduce liver damage
A hormone found in the stomach reduces inflammation and could ease liver diseases such as cirrhosis, research on rats has revealed.
HIV vaccine ready for human trials
Using a deactivated form of HIV as a vaccine may be the best new treatment for fighting the HIV virus, concluded scientists after studying primate responses to the treatment.
Handy information about animal research
Six new leaflets have been published by Understanding Animal Research, providing an overview of aspects of animal research
Brain development timing crucial for Fragile X
Slower brain development may be the reason some children reject all physical affection, research on mice has shown.
Dialogue is key?
In a febrile atmosphere, a 'panel discussion' took place on a Californian campus earlier this week between antivivisectionists and research advocates
Gene linked to premenstrual disorder
Premenstrual disorder may be linked to a specific gene, research on mice has shown.
Anaesthetic stops pain not movement
A novel anaesthetic that can stop pain yet allows patients to retain movement has been discovered through a study using rats.
House of Lords debate revision of EU regulations
On Wednesday, the House of Lords ‘took note' of a committee report into the revision of the EU Directive on the protection of animals used for scientific purposes
Mystery of Valium addiction revealed
Drugs such as Valium and Xanax could be redesigned after a study on mice has revealed the mechanism which makes them addictive.
Osteoporosis 'pill' success
Taking a special ‘bone pill' could be the key to healing brittle bones, research on mice has shown.
Effects of ageing in mice reversed using blood
Old mice have had their bone marrow rejuvenated after receiving blood supplies from younger mice, a new study has revealed.
Review of research regulations
This month has seen publication of the long-awaited Hampton Implementation Review Report for the Animals (Scientific Procedures) Division and Inspectorate.
Anti-depressant successful on stressed rats
Symptoms of depression caused by an inflammatory response could be alleviated by a new treatment, a study on rats has shown.
Skin cells to brain cells for better treatments
Skin cells have been transformed directly into functioning brain cells for the first time in a new study using mice.
Public opinion polling: what is it for?
A paper in the January 2010 Journal of Biomedical Ethics gives an interesting insight into the use of public opinion polls by all sides in the UK animal research debate.
BUAV student guide economical with the truth
What is wrong with animal experiments? asks BUAV's new ‘guide for students' and it is a question worth asking.
Bad design or bad reporting?
Critiques of animal research usually focus on issues such as the need for the study, the number of animals used, and how they are treated.
Pregnancy malaria risk shows need for research
A new study which estimates that approximately 60% of global pregnancies are at risk from malaria will highlight the need for continued research into treatments for the disease.
Exercise boosts brain power
Running a few days a week can stimulate the brain to grow new cells, research on mice has revealed.
Zebrafish are good models for human disease
Recent studies show zebrafish to be a useful animal model in studying mental illness and neurological diseases.
Eyes and sense of smell could act as indicators of Alzheimer's
Examining patients eye cells and ability to smell may help detect Alzheimer's disease earlier on, research on mice suggests.
Sharing the pie: new animal numbers activity for schools
How much do you know about which animals are used most in medical research and which are used least? Sharing the Pie, the latest addition to the Learning Centre's suite of activities for schools, is a fun way to find out.
New drug reverses effects of stroke
Stroke victims could regain near complete restoration of movement thanks to a new drug, research on rats has shown.
Potential cause of migraine identified
Rays of light act as a potential trigger for migraine attacks, a study on rats has found.
Science and the media – a call to action
Act now to safeguard improvements in science reporting – that is the message to the scientific community and government in the UK from a new strategic report published today.
Double bill in The Times for animal research
Most recently the Sunday Times cover piece last weekend took an in depth look at what goes on in animal labs in the UK, and the issues behind the research.
Radiation benefits for Alzheimer's mice
Mobile phone radiation has been found to decrease the severity of Alzheimer's disease in mice, according to new research.
Leukaemia vaccine ready for patients
A new vaccine which successfully treated mice with leukaemia will undergo the first human trials this year.
Pork products aid foetal mouse brain development
Eating pork that contains a micronutrient could help a growing brain develop, according to a recent study on mice.
Gel may help heart disease patients
A gel made of compounds found naturally in the body could be used to grow new blood vessels, research on rats has shown.
Gene therapy eases breathing problems
Delivering genes to specific cells which cause the lung disease emphysema could be key to alleviating breathing difficulties, research on mice suggests.
Rabies vaccine protects monkeys against HIV
A vaccine based on the one used to prevent rabies can be used to protect against the monkey form of HIV (SIV), a new study has found.
Artificial blood cells help clotting
Patients who are unable to form blood clots could be aided by a newly designed blood cell, research on rats has found.
Abnormal body clock linked to heart disease
High blood pressure may be linked to disruptions in the circadian body clocks, a study on mice suggests.
Childhood diabetes, food sweetener link
A new study has shown that the food sweetener fructose can cause dangerous body fat deposits and trigger diabetes and heart disease in humans.
Loneliness linked to cancer in rats
Loneliness and stress are more likely to cause breast cancer, a study using rats suggests.
Great blog, but sadly anonymous
Here in the Understanding Animal Research office we were delighted to read this well written and interesting blog titled ‘Why we experiment on animals' on the Times newspapers new science site Eureka Zone.
Novel treatment to tackle Hepatitis C
Targeting host molecules instead of the virus has proved successful in killing the Hepatitis C virus (HCV), research on chimpanzees has found.
Missing link found in foetal heart failure
The inability to form a blood clot in a foetal blood vessel has been linked to heart failure in newborns, a study using mice has discovered.
Stem cell therapy restores vision in rats
Vision in blind rats has been restored by a UK team in collaboration with international scientists.
New virus helps combat brain tumours
Aggressive brain tumours can be killed and prevented from recurring using a virus, a new study using mice has found.
Stomach hormone protects against Parkinson’s disease
A study involving mice has revealed that a hormone originating in the stomach has a new use in boosting resistance to Parkinson's disease.
Cancer vaccine implant success in mice
A cancer ‘vaccine' which can be implanted under the skin and instructs the body to attack tumour cells has proved successful in experiments with mice.
Blood transfusion between animals - one of science's oldest iconic papers now online
The new Trailblazing scheme from the Royal Society sheds light on some of the most iconic scientific discoveries of all time, and allows users to access digitised versions of these iconic scientific papers.
Why a little bit of dirt never harmed anyone
‘Friendly' bacteria living on the skin can be beneficial to our health, according to new research using mice and human cells.
Ten years old and nothing gained
The animal rights extremist group SHAC is 10 years old this month. But the activists who fly this flag have nothing to celebrate.
Will we hear the sound of music again?
Julie Andrews, the star of musicals Mary Poppins and The Sound of Music has announced she will return to the London stage next year after more than 30 years.
Better understanding of need for new brain cells
Scientists know that the adult brain continues to create new nerve cells (neurons), but the reason why this happens is poorly understood.
Artificial skin from stem cells for fast burn treatment
Sheets of 'substitute skin' from human embryonic stem cells have been grafted onto mice in the laboratory.
Biomatrix may allow tumour testing without mice
Mice are used widely in the study of cancer and to test the clinical efficiency and safety of anti-cancer therapies.
New MS treatment for spinal cord injury?
Researchers have made a step forward in treating nerve cells damaged in spinal cord injuries, using guinea pig tissues.
Unlimited supply of rare cells produced in the lab
A new method to treat arthritis has proven successful in mice, and holds strong hopes for treating other autoimmune disorders.
Rock band unleashes violence tirade at UK gig
We aren't sure if it's because it was Friday the 13th but unlucky Flaming Lips fans were faced with an unpleasant display at a gig in Portsmouth last week.
Lung tumour treatment shows promise
Researchers have discovered a new medicine which is able to stop lung tumours from growing in mice, even eliminating them altogether in half of all cases.
Lords take balanced approach but concerns remain
Understanding Animal Research welcomes the report published this week by the House of Lords EU Committee.
Considering what it is to be human
The Academy of Medical Sciences has launched a new project to examine the use of animals containing human material in scientific research.
Damaging effects of fat reversed
Researchers have long known that overweight people are more likely to develop conditions such as diabetes and heart disease.
Gene therapy repairs damaged lungs
Using outside-the-body gene therapy in pig and human lungs, researchers have repaired donated organs that were deemed too damaged to transplant.
Infiltration raises questions
The recent infiltration of a UK safety testing facility by an antivivisectionist raises many questions.
Gene therapy promise for muscular dystrophy
Scientists have developed a new gene therapy successful in treating the most severe type of muscular dystrophy in mice.
High-protein diet shrinks brain
Past research has suggested that high protein diets, such as the Atkin's diet, can increase the risk of heart disease and kidney problems.
Loose laws and bad judgements
Weighing up the cost to animals and the potential benefit of any particular research program is no simple task.
Five years ago newspaper reports of medical breakthroughs rarely mentioned the animal research that had played a part in creating a medicine or treatment.
Towards replacing rabbit eye tests
Two new 'non-animal methods', have now been approved by OECD for testing the irritancy of some substances to the eye.
Dogma would deny dogs new cancer drug
Antivivisectionists have spoken out against giving dogs with cancer a new cancer drug.
When the going gets tough...
We have seen in the UK that, when attacked by violent animal rights extremists and vociferous antivivisectionists...
Beating heart muscle engineered
Scientists have grown a thin strip of heart muscle, which is able to beat spontaneously, using stem cells from a mouse embryo.
Gene therapy treats Parkinson’s tremors
Researchers have used gene therapy to correct movement problems in macaque monkeys with Parkinson’s symptoms.
Cholesterol beneficial to brain cell development
Researchers have discovered that a derivative of cholesterol is necessary for forming brain cells.
Healing properties of stem cells improved
In a mouse study, scientists have engineered stem cells to enhance their healing properties.
Longer life for donated hearts
A discovery in pigs could increase the number of transplants that can be performed.
Longer, healthier lives for mice
Scientists have extended the lifespan of mice by manipulating their genomes.
Treating brain secondaries in mice with breast cancer
Scientists have shown that the drug vorinostat is able to cross the blood-brain barrier, and reduce the development of brain tumours in mice.
Lack of sleep linked to Alzheimer's
Studies using mice suggest that lack of sleep could increase the development of plaques in the brain, accelerating the development of Alzheimer’s disease.
White blood cells set the pace of wound repair
After more than 50 experiments in mice, scientists have mapped out how a set of white blood cells (lymphocytes) set the pace of recovery after serious lung injury.
UK Bioscience submits supplementary evidence to the House of Lords European Union Committee Inquiry
The UK Bioscience sector prepared a submission of supplementary evidence to the House of Lords European Union Committee, Sub –Committee D (Environment and Agriculture) on the revision of Directive 86/609.
Time for more change in America
We have been watching with great concern the animal rights extremists’ campaigns taking place in the United States and California in particular.
'Master gene' for immune cells identified
Researchers have identified the master gene that causes blood stem cells to turn into natural killer (NK) immune cells.
Gene therapy for colour blindness
A team of scientists have restored colour vision to two colour blind squirrel monkeys using gene therapy.
Stem cell link to prostate cancer
A new study identifies a stem cell that may cause some types of prostate cancer, at least in mice.
How broccoli protects arteries
Researchers have discovered one reason why broccoli and other green leafy vegetables are definitely good for you.
New research shows public opinion supportive of animal research
The latest public opinion research from Ipsos MORI shows that the vast majority of the British public can accept animal experimentation for medical research purposes.
Pioneers of stem cell research in animals win 'pre-Nobel'
The 2009 Albert Lasker basic medical research prize has just gone to stem cell pioneers John Gurdon and Shinya Yamanaka for their work using frogs and mice.
EU tries to avoid using 54 million more animals
A recent study suggests that the chemical industry will have to spend €9.5 billion (US$13.6 billion) on safety testing over the next decade.
Diesel fumes grow new blood vessels?
New findings indicate that the link between diesel exhaust fumes and cancer lies in the ability of particles within the exhaust fumes to cause the growth of new blood vessels, which can aid tumour development.
The Shuffle: new interactive
Understanding where medicines come from – the long process from basic research, through clinical trails, to licensing and prescription – is not always easy for professional researchers, let alone young people.
Key protein in obesity related diseases
It is well known that obesity can lead to health problems such as diabetes and cardiovascular disease, and it is thought that this is due to low-grade inflammation.
Balanced diet best for arteries
A team studying the effect of diet on the cardiovascular system in mice have shown that a diet low in carbohydrates could lead to artery damage.
Monkeys with two mums may eradicate mitochondrial disorders
Scientists have produced four infant monkeys using a technique which could stop women with genetic diseases passing them on to their children.
Patching a broken heart
A team of scientists have developed a patch which could help the heart to heal after damage.
Leishmania parasites feed immune cells
Researchers using mice have shown how the Leishmania parasite, transmitted by sand flies, establishes infection.
'Magnetic' stem cells target damaged blood vessels
Scientists have harnessed the power of magnetism to guide stem cells towards damaged tissue in rats.
New target for stopping colon cancer
A team of scientists studying mice have found a target that could lead to an effective way to kill colon cancer cells.
Delaying motor neurone disease
By blocking the production of a faulty protein in mice, researchers have delayed the onset of motor neurone disease, improved mobility, and extended life-span.
How infection can lead to psychiatric problems
Scientists using mice have discovered how early exposure to a common type of bacterium can lead to psychiatric disorders.
Nanobees deliver deadly sting
A group of scientists has harnessed the power of bee venom and used it to kill tumour cells in mice.
Schools drama released on DVD
Every Breath, an award-winning drama-based set of teaching resources from Y Touring Theatre Company is now available on DVD, free to schools.
Stopping cancer spreading
Working with 'substitute' breast cancer stem cells and mice, scientists have discovered a chemical which can kill the cells that cause tumours to spread and return, even after seemingly successful treatment.
Glaucoma reversed in rats and humans
Researchers have reversed the symptoms of glaucoma in rats using medicated eye drops.
Heart stimulated to heal itself
Scientists have shown for the first time that it is possible to stimulate the heart to heal itself without the use of stem cell technology.
Rodent teeth grow from stem cells
Mice have grown new teeth from stem cells implanted into the jawbone.
The editorial in today's Financial Times about responding to the appalling animal rights extremist attacks in Switzerland is spot on.
Chimps get AIDS too
Scientists have discovered that the natural hosts of a strain of SIV develop AIDS when infected.
Food dye aids spinal crush injury
A blue dye – similar to that used in M&Ms and liquorice allsorts – can help protect rats' crushed spinal cords from further damage.
Skin stem cells make mouse clones
A new kind of stem cell, that doesn't involve destroying embryos, has produced new life.
Snails, slime moulds and flies
Government funding for alternatives research, through NC3Rs, has nearly doubled this year compared with 2008.
Gene controller causes Down syndrome
Researchers have used mice to pinpoint what goes wrong in aneuploidy, which includes the most common genetic disorders involving chromosomes, usually an extra chromosome.
New way to reduce anaphylactic shock
Using mice, scientists have pinpointed the molecule which is responsible for making allergic reactions more severe.
Swine flu research
Our own modest contribution to swine flu information is now online, as the government estimates the number of new cases of swine flu in England reached 100,000 in the past week.
What do they know?
We recently became aware of a new website that can be used to make Freedom of Information requests and acts as an archive for all information received.
More research means more animals
The 2008 figures for use of animals in UK research were released today by the Home Office.
PeTA boobs again
The latest completely irresponsible PeTA campaign uses a crass computer game to push its 'breasts not animal tests' message to children. The web is all a-twitter with reviews panning the game.
UK bioscience sector publishes detailed response on European regulation
A dozen organisations representing UK bioscience have published their answers, many of them detailed, to 72 questions posed by the UK Home Office.
Caffeine halts Alzheimer's
Using GM mice, scientists have shown that caffeine can reduce dementia symptoms.
Hype, hope and hybrids
The three-year public debate in the UK on animal-hybrid embryos was always a secondary issue for Understanding Animal Research and its forerunners, but an important one.
A TV dramatisation of Edwardian antivivisection protest on Sunday night in Casualty 1909 shows there's little new in the public debate over animal research and testing.
40,000 trout undercut costs, increase accuracy
The largest animal study ever on the cancer-causing risk (carcinogenicity) of chemicals could have profound implications for the species used in such testing, the numbers of animals used, and the accuracy of current tests.
Gene suppression in type 2 diabetes
Blocking the action of a gene called Sirtuin-1 reduced the symptoms of type 2 diabetes in rats, scientists have found.
The National Centre for the Three Rs has produced a handy 'beginners guide' to the 3Rs - Refinement, Reduction and Replacement - and how they can benefit science, innovation and animal welfare.
Targeting skin cancer
Using fish, scientists have discovered a signalling pathway that could be used to treat skin cancers (melanomas).
A tale of three species
The law of unintended consequences may have led to saving rabbits at the expense of a two incredible species: a prehistoric invertebrate and a small bird with one of the most impressive known migrations.
GM mice get Parkinson's disease
Researchers have created a GM mouse that develops Parkinson's disease.
Novel gene therapy reverses haemophilia
Scientists using mice have developed a new way to deliver gene therapies.
An Odyssey exploring the debate
A book to be published soon promises a considered, less polarised approach to the animal rights debate.
Protein culprit in Huntington's disease
Why does Huntington's disease lead to the death of brain cells, whilst causing negligible damage to cells elsewhere in the body?
Nanoparticles seek out plaques in arteries
Researchers have designed small particles - ‘nanoparticles' - that are able to selectively bind to plaques in arteries.
Effect of breast cancer gene reversed
Scientists have identified a gene implicated in up to one fifth of breast cancers. The good news is that studies in mice seem to show a commonly-used blood pressure drug appears to reverse the effects of the gene.
Pig cells transplant potential
Scientists have found a way to turn adult cells from pigs into any tissue in the body.
UK bioscience sector submits evidence to Lords
The House of Lords European Union Committee, Sub-Committee D (Environment and Agriculture) has begun to take oral evidence on the revision of the European Directive on animal experimentation