Mice are the most commonly used vertebrate animals in medical research. This trend looks likely to continue now that both mouse and human genomes have been mapped (80% of human genes are exactly the same as those found in mice, and at least a further 10% are very similar) allowing human genetic disorders and diseases to be studied with greater accuracy. Often, the only way of determining the function of a human gene is to insert it into, or remove it from, the mouse genome. Many thousands of mouse strains now exist, some frozen as embryos. Eventually, such techniques could lead to new methods of preventing, treating or even curing genetic diseases and other diseases with a genetic component. 87% of all genetically modified animals used in research in the UK are mice [UK 2018 figures].
See also our pages on GM mice and breeding, mice and stem cell research, our video of mice, and animal research.info on mice and GM mice.